St. Matthews Animal Clinic Introduce
For decades, pet parents across Louisville, Kentucky, have trusted St. Matthews Animal Clinic (SMAC) as a comprehensive resource for their companion animals' health, wellness, and comfort. Since its founding over 40 years ago, SMAC has established itself as a cornerstone of the St. Matthews community, embodying a commitment to advanced medical care coupled with compassionate, personalized service. As a full-service animal hospital, it moves beyond routine check-ups to offer a wide array of specialized services, including advanced diagnostics, emergency medicine, and even therapeutic treatments like laser acupuncture and stem cell therapy.
Operating as a women-owned practice, the clinic is deeply invested in the local community and offers a uniquely inclusive and caring environment for pets and their owners. The dedicated veterinary staff, including skilled veterinarians like Dr. Michalski, are often praised by clients for their patience, knowledge, and willingness to work through complex or terminal issues with great follow-up care. Whether your pet is a playful puppy, a geriatric companion, or a fascinating exotic animal, the team at St. Matthews Animal Clinic is equipped to provide the highest standard of care.
Recognizing that pet care extends beyond the examination room, SMAC provides convenient on-site services such as full-service pet boarding and professional grooming. This integration of medical and non-medical services under one roof is a significant benefit for busy Kentucky families, offering a single, trusted location for all their pet care needs.
St. Matthews Animal Clinic is conveniently situated in the heart of the St. Matthews neighborhood in Louisville, Kentucky. This central location makes it highly accessible from surrounding areas like Crescent Hill, Lyndon, and Middletown.
- Address: 111-R Fairfax Ave, Louisville, KY 40207, USA
- Primary Phone: (502) 895-8100
- Mobile Contact: +1 502-895-8100
Accessibility is a key priority for the clinic, which features a wheelchair-accessible entrance, parking lot, and restroom, ensuring that all community members can easily access their services. The clinic is open seven days a week for pet care needs, with extended morning and evening hours during the week to accommodate working families. While appointments are recommended for veterinary services, the clinic strives to accommodate walk-ins and same-day appointments for established clients, especially for urgent medical situations, highlighting its dedication to emergency service.
St. Matthews Animal Clinic provides an extensive range of medical and comfort services for dogs, cats, and exotic animals, positioning it as a true full-service animal hospital in the Louisville area.
- Complete Veterinary Medicine and Diagnostics:
- Annual Examinations and Wellness Visits.
- In-House Laboratory Services (Complete Blood Count, Chemistries, Fructosamine, Phenobarbital Level).
- Advanced Imaging (Digital Radiography, Digital Radiology, Ultrasound, Pet Echocardiogram).
- Internal Medicine and Disease Prevention.
- Senior Pet Care and Nutritional Counseling/Weight Management.
- Curbside Service and Drop-Off Appointments for convenience.
- Preventive Care and Vaccination Programs:
- Pet Vaccinations (Dogs Rabies Vaccine, Distemper, Canine Influenza, Leptospirosis Vaccine, Lyme Vaccine, Feline Leukemia Vaccine, Kitten and Puppy Vaccines).
- Parasite Prevention and Testing (Heartworm Test, Intestinal Parasite Screen, Dog flea and tick treatment).
- Microchip Pet ID placement.
- Advanced Surgery and Dentistry:
- General Veterinary Surgery (Neuter, Growth Removal, Mass Removal, Exploratory Surgical procedures).
- Specialized Surgery (Laser Surgery, Oral Surgery, Extractions).
- Comprehensive Pet Dentistry (Dental Health, Dental Radiographs, Dogs Dental Care).
- Pet Euthanasia with compassionate support.
- Specialized and Therapeutic Treatments:
- Emergency Medicine and Pet Emergency Services.
- Pet Therapeutic Laser, Laser Treatment, and Laser Acupuncture for pain relief and inflammation (including for Arthritis).
- Pet Stem Cell Therapy (a cutting-edge option for joint and degenerative conditions).
- Full-Service Pet Comfort and Care:
- Pet Boarding and Daycare (Kennel services available 7 days a week, including a Patient Care Team for close supervision).
- Professional Pet Grooming (Dog grooming, Dog nail trimming, Dog anal gland expression).
- Pet Pharmacy and convenient Online Pharmacy options.
- House Calls (available for select services).
- Exotic Animal Care:
- Veterinary services are extended to exotic animals, making it a valuable resource for owners of non-traditional pets in Kentucky.
St. Matthews Animal Clinic is defined by its full-spectrum care model and exceptional commitment to client service, making it a preferred choice for comprehensive pet care in Louisville.
- True Full-Service & Emergency Capability: Unlike limited-service clinics, SMAC is an accredited animal hospital offering everything from routine wellness to sophisticated surgical, diagnostic, and emergency medical treatment, providing continuity of care throughout a pet’s life.
- Advanced Therapeutic Options: The inclusion of cutting-edge services such as Pet Stem Cell Therapy, Laser Acupuncture, and Therapeutic Laser treatments showcases the clinic's commitment to modern, less-invasive pain management and healing for conditions like arthritis and inflammation.
- Convenient All-in-One Pet Hub: The seamless integration of full-service veterinary care with on-site pet boarding, day care, and professional grooming allows Kentucky pet owners to manage all their pet's needs in one trusted location. Boarding drop-offs and pick-ups are available 7 days a week.
- Dedicated to Compassion and Communication: Customer reviews consistently highlight the patient, compassionate vets and staff who are thorough, knowledgeable, and provide great follow-up, ensuring anxious owners feel informed and their "fur babies" feel safe.
- Accessibility and Inclusivity: The business is women-owned and explicitly LGBTQ+ friendly, prioritizing a welcoming atmosphere for all members of the Louisville community. They also offer excellent physical accessibility with wheelchair-friendly features.
- Accepts Insurance and Financing: To help manage healthcare costs, the clinic accepts major forms of pet insurance and partners with payment solutions like CareCredit, making high-quality, necessary care more financially manageable.
For Kentucky pet owners seeking a veterinary partner that offers both comprehensive medical excellence and the convenience of integrated pet services, St. Matthews Animal Clinic stands out. Choosing SMAC means selecting a practice with deep roots in the community and a history of providing compassionate, complete veterinary care for over four decades. The facility’s commitment to advanced medicine—such as digital radiology, ultrasound, and therapeutic lasers—ensures that your beloved dog, cat, or exotic animal receives modern, top-tier care.
What truly sets them apart is the ability to handle every facet of a pet's life journey, from initial puppy vaccines and annual wellness checks to complex emergency surgeries and compassionate end-of-life care. The added convenience of having supervised pet boarding and professional grooming on-site is an enormous practical benefit, simplifying pet management for busy families. Pet parents often point to the personal connection, noting that the veterinarians and staff are dedicated to follow-up and patient education, ensuring they are not just treating a symptom but caring for the whole pet. The inclusion of services for exotic animals also fills a crucial need in the Louisville region. For a trusted, full-service, and exceptionally compassionate animal hospital experience, St. Matthews Animal Clinic is the clear choice.
Kentucky residents are encouraged to call ahead to schedule appointments for veterinary services, though walk-ins and same-day emergency services are often accommodated.
- Address: 111-R Fairfax Ave, Louisville, KY 40207, USA
- Phone: (502) 895-8100
- Mobile Phone: +1 502-895-8100
St. Matthews Animal Clinic Services
Pet Groomer
- Dog anal gland expression
- Dog flea and tick treatment
- Dog grooming
- Dog nail trimming
Kennel
- Dog walking
Veterinarian
- Exotic animals
- Animal Clinic
- Annual Blood Work
- Annual Examination
- Arthritis
- Boarding & Daycare
- Bordetella Vaccine
- Canine Influenza
- Cats Dental
- Chemistries
- Compassionate Vets
- Complete Blood Count
- Complete Veterinary
- Complete Veterinary Care
- Curbside Service
- Cytology
- Dental Health
- Dental Radiographs
- Dentistry Digital Radiography
- Dentistry Including Dental Radiographs
- Digital Radiography
- Digital Radiology
- Digital Radiology, Ultrasound
- Disease Prevention
- Distemper Vaccines
- Dogs Cats
- Dogs Rabies Vaccine
- Dogs and cats
- Drop-Offs
- Exotic Animal
- Exploratory Surgical
- Extractions
- Feline Leukemia Vaccine
- Fructosamine
- General Veterinary
- General Veterinary Surgery
- Growth Removal
- Heartworm Test
- Home Remedies
- Hospitalization
- House And Online Pharmacy
- In-House Laboratory
- Inflammation
- Internal Medicine
- Intestinal Parasite
- Intestinal Parasite Screen
- Joint Supplement
- Kitten Vaccines
- Lab Test
- Laser Acupuncture
- Laser Surgery
- Leptospirosis Vaccine
- Lyme Vaccine
- Lyme Vaccines
- Mass Removal
- Medical Treatment
- Medicine For Pets
- Microchip Pet
- Neuter
- Non-Steroidal Anti-inflammatories
- Nutritional Counseling
- Online Pharmacy
- Oral Surgery
- Pet Boarding
- Pet Day Care
- Pet Dentistry
- Pet Digital Radiography
- Pet Echocardiogram
- Pet Emergency Services
- Pet Euthanasia
- Pet Grooming
- Pet Health
- Pet Health Care
- Pet In Clinic Laboratories
- Pet Insurance
- Pet Kitten Care
- Pet Microchip
- Pet Nutrition
- Pet Pain Relief
- Pet Pharmacy
- Pet Poison Control
- Pet Puppy Care
- Pet Records
- Pet Stem Cell Therapy
- Pet Surgery
- Pet Surgical
- Pet Surgical Laser
- Pet Therapeutic
- Pet Therapeutic Laser
- Pet Ultrasound
- Pet Vaccinations
- Pet's Diet
- Pet's Health
- Pet's Records
- Phenobarbital Level
Animal Hospital
- Blood Work
- Canine Vaccine
- Dogs Dental Care
- Emergency Medicine
- House Calls
- Laser Therapeutic
- Laser Therapy
- Laser Treatment
- Medical Services
- Parasite Prevention
- Preventative Medicine
- Puppy Vaccines
- Senior Pet Care
- Vet Services
- Veterinary Dentistry
- Weight Management
St. Matthews Animal Clinic Details
From the business
- Identifies as women-owned
Service options
- Onsite services
Accessibility
- Wheelchair accessible entrance
- Wheelchair accessible parking lot
- Wheelchair accessible restroom
Amenities
- Restroom
Crowd
- LGBTQ+ friendly
Planning
- Appointments recommended
St. Matthews Animal Clinic Photos










St. Matthews Animal Clinic Location
St. Matthews Animal Clinic
111-R Fairfax Ave, Louisville, KY 40207, USA
St. Matthews Animal Clinic Reviews
babyfeelfurpaygroomingcheckupsundaymatterdeskmorning
★ 5★ 4★ 3★ 2★ 1My favorite veterinary practice. Extremely knowledgeable and experienced as well as patient with difficult pets and their anxious owners who have 30 questions every visit. Great follow up on pets with bigger/terminal issues. Can't say enough wonderful things about SMAC!
October 06 · annie appelhofBest animal clinic ever. Dr Michalski and her staff always took wonderful care of my fur baby, even though he was a little terror. Sadly, he has gone to the rainbow bridge but I will continue to recommend this office to anyone. Thank you all for always taking excellent care of Lucky. You all are the best!,,
June 29 · Fronni ParkerThey saved our beloved cat, Ollie, by performing emergency surgery on extremely short notice when other local providers could not. We will be forever grateful for both their compassion and technical skills in veterinary medicine.P.S. he’s back to his usual bad self. But I think he appreciates it as well!
October 03 · Mitchell HadleyIf you’re wanting to feel listened to about your pet concerns & feel like your vet is taking the time to understand you, Dr. Stacy Deren is not your girl. She literally smiled & laughed in my face mid question & when I told her that was very dismissive she didn’t even think to apologize. Instead told me I could take it that way if I wanted… The best thing I got out of the appointment were recommendations for other vets. 😂 Definitely don’t recommend.
July 15 · Hannah SmithI cannot say enough wonderful things about this practice. They have been caring for my dogs since 2018 and have helped me navigate the challenges of their aging so thoughtfully. They are so passionate about the animals that they take care of and always take as much time as needed to answer questions and provide insight. Dr. McCoy has been amazing through the years as their main provider. I had the pleasure of meeting Dr. Barney yesterday and she was also wonderful, extremely thorough, and kind. I am very grateful for the entire team at St. Matthew’s Animal Clinic! Thank you all for the wonderful care you provide!
March 08 · Sarah Claeys
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